References

References

  1. American Academy of Family Physicians. Heartburn. 1996. http://familydoctor.org/familydoctor/en/diseases-conditions/heartburn/causes-risk-factors.html (accessed 5 June 2013)
  2. American Academy of Family Physicians. Antacids and Acid Reducers: OTC Relief for Heartburn and Acid Reflux. 2012. http://familydoctor.org/familydoctor/en/drugs-procedures-devices/over-the-counter/antacids-and-acid-reducers-otc-relief-for-heartburn-and-acid-reflux.html (accessed 5 June 2013)
  3. American College of Gastroenterology. Acid reflux. 2013. http://patients.gi.org/topics/acid-reflux/ (accessed 8 April 2013).
  4. American College of Physicians. ACP Special Report. Understanding and treating heartburn. 2013. (accessed 8 April 2013).
  5. Canadian Digestive Health. Statistics. 2012. http://www.cdhf.ca/digestive-disorders/statistics.shtml (accessed 8 April 2013).
  6. Canadian Digestive Health Foundation. Acid reflux and GERD: The unsettling reality in Canada. 2009. http://www.cdhf.ca/bank/document_en/45-acid-reflux-gerd.pdf (accessed 22 Jan 2014).
  7. Canadian Institute for Health Information. Proton Pump Inhibitor Use in Seniors: An Analysis Focusing on Drug Claims, 2001 to 2008. https://secure.cihi.ca/free_products/PPI_aib_en.pdf (accessed 24 March 2014).
  8. Health Canada. Canadian Adverse Reaction Newsletter, Volume 21 - Issue 3 - July 2011. http://www.hc-sc.gc.ca/dhp-mps/medeff/bulletin/carn-bcei_v21n3-eng.php (accessed 24 March 2014).
  9. Mayo Clinic. Heartburn. 2011. http://www.mayoclinic.com/health/heartburn-gerd/DS00095 (accessed 8 April 2013).
  10. Mayo Clinic. GERD. 2012. http://www.mayoclinic.org/diseases-conditions/gerd/basics/definition/con-20025201 (accessed 22 Jan 2014).
  11. National Digestive Diseases Information Clearinghouse. Heartburn, Gastroesophageal Reflux (GER), and Gastroesophageal Reflux Disease (GERD). Update 2012. http://digestive.niddk.nih.gov/ddiseases/pubs/gerd/#1 (accessed 5 June 2013).

Glossary of Terms

Acid Reducers: Acid reducers are often called H2 blockers. H2 blockers turn off one of the three signals that activate the acid pumps in the stomach. This blocks the release of a portion of the pump’s acid. While they don’t relieve symptoms right away, H2 blockers relieve symptoms for a longer period of time than antacids.

Antacids: Antacids partially neutralize excess stomach acid; they provide rapid but short-term relief lasting up to two hours.

Bisphosphonates: Bisphosphonates are a class of drugs used to treat osteoporosis.

Gastroesophageal Reflux Disease (GERD): GERD, a chronic digestive disease, is a serious form of acid reflux. This condition causes food or stomach acid to come back up from the stomach into the esophagus. This backwash of acid can irritate the lining of the esophagus, causing heartburn and a variety of other symptoms. OLEX is not indicated for use in patients with GERD.

Hiatus (Hiatal) Hernia: A hiatal hernia occurs when part of your stomach is pushing upward through your diaphragm. A large hiatal hernia can cause food and acid to back up into your esophagus, resulting in heartburn.

Iron Salts: Iron salts are used to treat iron deficiency (usually used to treat anemia). In addition to the elemental iron, the iron salt content may also include ferrous sulfate, fumarate, or gluconate.

Lower Esophageal Sphincter (LES): The LES is a circular band of muscle around the lower part of your esophagus; it relaxes to allow food and liquid to flow into your stomach and then closes again.

Obesity: An obese person has a Body Mass Index (BMI) of 30 or above. Pressure on the stomach and diaphragm due to excess weight can cause the LES to open and allow stomach acid into the esophagus, causing heartburn.

Potassium Salts: Potassium salts are electrolytes used to replace potassium loss in the body.

Pregnancy: Greater abdominal pressure during pregnancy as well as an increase in progesterone can cause the LES to relax and lead to heartburn.

Proton Pump Inhibitors (PPIs): PPIs reduce stomach acid by suppressing acid pumps in the stomach, despite this suppression of acid, normal digestion of food can still take place.